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Feline Immunodeficiency Virus, p24 gag (FIV)

Feline Immunodeficiency Virus, p24 gag (FIV)

Cat no: F0030-15D

Supplier: United States Biological
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The lentivirus FIV, responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency Virus (HIV), is a complex retrovirus with a tightly-packed genome, containing the structural genes gag, env and pro-pol and the accessory genes vif, rev and ORF-A/2. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F0030-15D
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 250ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
References: 1. Lerner, D.L. et al. (1995) Increased mutation frequency of Feline Immunodeficiency Virus lacking functional deoxyuridine-triphosphatase. Proc. Natl. Acad. Sci. 92: 7480-7484.2. Chatterji, U. et al. (2000) Feline Immunodeficiency Virus Vif localises to the nucleus. J. Virol. 74: 2533-2540.3. Norway, R. M. et al. (2001) Thymic lesions in cats infected with a pathogenic molecular clone or an ORF-A/2 -deficient molecular clone of Feline Immunodeficiency Virus. J. Virol. 75: 5833-5841.4. Simon, J.H.M. et al. (1997) The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells. J. Virol. 71: 5259-5267.
Additional info: Recognizes a p24 epitope of feline immunodeficiency virus (FIV) p24 gag. Does not recognize Feline Leukemia Virus (FeLV), Feline Herpes Virus (FHV) type 1, Feline Coronavirus or Feline Calicivirus.

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