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FGF-19, Recombinant, Human (His) (Fibroblast Growth Factor 19)

Cat no: 044795

FGF-19, Recombinant, Human (His) (Fibroblast Growth Factor 19)

FGF-19 (Fibroblast growth factor 19) is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.\n\nBiological Activity:\nActivates ERK and FRS2alpha phosphorylation in rat hepatoma cells.\n\nSequence:\nSignal peptide and human FGF-19 (aa 1-216) are fused at the C-terminus to a His-tag.\n\nStorage and Stability:\nShort-term Storage: +4 degrees C\nLong-term Storage: -20 degrees C\nWorking aliquots are stable for up to 3 months when stored at -20 degrees C.

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SPECIFICATIONS

Catalog Number

044795

Size

10ug

Form

Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.

Purity

>90% (SDS-PAGE)

Alternative Names

Fibroblast Growth Factor 19

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