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FGF17, Recombinant, Human, aa23-216, His-Tag (Fibroblast Growth Factor 17, FGF-13)

Cat no: 137057

FGF17, Recombinant, Human, aa23-216, His-Tag (Fibroblast Growth Factor 17, FGF-13)

FGF17 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was shown to be prominently expressed in the cerebellum and cortex. The mouse homolog of this gene was localized to specific sites in the midline structures of the forebrain, the midbrain-hindbrain junction, developing skeleton and developing arteries, which suggests a role in central nervous system, bone and vascular development. \n\nSource: \nRecombinant protein corresponding to human FGF17, fused to His-tag at N-terminal expressed in E.coli.\n\nMolecular Weight: \n~25.2kD (219aa) \n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSHMTQGEN HPSPNFNQYV RDQGAMTDQL SRRQIREYQL YSRTSGKHVQ VTGRRISATA EDGNKFAKLI VETDTFGSRV RIKGAESEKY ICMNKRGKLI GKPSGKSKDC VFTEIVLENN YTAFQNARHE GWFMAFTRQG RPRQASRSRQ NQREAHFIKR LYQGQLPFPN HAEKQKQFEF VGSAPTRRTK RTRRPQPLT\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137057

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.4M urea,10% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Zhang X., et al. (2006) J. Biol. Chem. 281:15694-15700. 2. Turner N., et al. (2010) Nat. Rev. Cancer. 10:116-129.

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