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Fibrinogen-like Protein 1 (FGL1, Hepassocin, Fibrinogen-like 1)

Fibrinogen-like Protein 1 (FGL1, Hepassocin, Fibrinogen-like 1)

Cat no: F4204-05

Supplier: United States Biological
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Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:16,000 Western Blot: 0.1-0.3ug/ml detects an~ 35kD band observed in Human Liver lysates (calculated MW of 36.4kD according to NP_004458.3). Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F4204-05
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: hepatocyte-derived fibrinogen-related protein 1, hepatocellular carcinoma-related sequence, hepassocin, OTTHUMP00000122468, MGC12455, LFIRE1, HP-041, HFREP1, fibrinogen-like 1, FGL1
References: 1. Liu Z, Ukomadu C, Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant. Biochemical and biophysical research communications 2008 Jan 365 (4): 729-34. PMID: 18039467
Additional info: Recognizes human FGL1. Species sequence homology: mouse, rat, canine, bovine.

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