Home  >  Products  >  Fibronectin, Plasma (pFn, FN, FN1, Cold-insoluble Globulin, CIG, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED-B, FINC, FNZ, GFND, GFND2, LETS, MSF)
Fibronectin, Plasma (pFn, FN, FN1, Cold-insoluble Globulin, CIG, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED-B, FINC, FNZ, GFND, GFND2, LETS, MSF)

Fibronectin, Plasma (pFn, FN, FN1, Cold-insoluble Globulin, CIG, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED-B, FINC, FNZ, GFND, GFND2, LETS, MSF)

Cat no: F4215-20P

Supplier: United States Biological
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Fibronectins are diverse high molecular weight cell adhesion glycoproteins found in basement membranes, in the interstitial connective tissue matrix, and in soluble in plasma and other body fluids. In adult tissues most fibronectin is produced by hepatocytes (pFn) that differ from locally produced cellular fibronectins. A monoclonal antibody (BF12)has been produced to fibronectin that reacts with both the cellular and plasma forms of the protein and recognizes the cell-binding region in fibronectin. The monoclonal antibody DH1 recognizes only cellular form of Fibronectin. DH1 is specific to the extra domain A (EDA) of the molecule. cFns are found in some basement membranes during development and only in distinct tissues in adult, for instance in smooth muscle and alveolar walls of airways. cFns are abundant in the plasma of carcinoma patients and in the stroma of various carcinomas. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: (same/more than)1:1000 Immunohistochemistry: Frozen Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F4215-20P
Reactivities: Human, Guinea Pig
Hosts: Mouse
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 1% BSA, 0.1 % sodium azide.
P type: Mab
Isotype: IgG1
Purity: Ascites
References: 1. Auranen M. et al. (2000) Neuromusc. Disord. 10, 16-23. 2. Vesaluoma M. et al. (1998) Eye 886-890. 3. Tuori A. et al. (1997) Graefe
Additional info: Recognizes the cellular and plasma forms of human fibronectin and recognizes the cell binding region. Species Crossreactivity: Guinea pig

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