Filensin (Beaded Filament Structural Protein 1, BFSP1, Lens Fiber Cell Beaded-filament Structural Protein CP 115, CP115, Lens Intermediate Filament-like Heavy, LIFL-H)

Applications: \nSuitable for use in ELISA, Western Blot and Immunofluorescence. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:1000-1:2000\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

F4510-95

Size

100ul

Applications

ELISA, IF, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Ch/Bird, Sheep

Form

0.1% Sodium Azide; Whole Serum

P Type

Mab

Purity

Ascites

Isotype

IgG1

References

Sandilands A et al. Filensin is proteolytically processed during lens fiber cell differentiation by multiple independent pathways. Eur J Cell Biol 67:238-53 (1995). <PUBMED:7588880>Sandilands A et al. Vimentin and CP49/filensin form distinct networks in the lens which are independently modulated during lens fibre cell differentiation. J Cell Sci 108 ( Pt 4):1397-406 (1995). <PUBMED:7615661>Georgatos SD et al. The beaded intermediate filaments and their potential functions in eye lens. Bioessays 16:413-8 (1994). <PUBMED:8080431>Merdes A et al. Filensin: a new vimentin-binding, polymerization-competent, and membrane-associated protein of the lens fiber cell. J Cell Biol 115:397-410 (1991). <PUBMED:1918147>

Additional Info

Species Crossreactivity: Crossreacts with Human, bovine and Sheep. Does not crossreact with Mouse, Rat or Chicken. Not yet tested in other species.