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FK-506 (Tacrolimus)

FK-506 (Tacrolimus)

Cat no: 012054

Supplier: United States Biological
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An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release. Form: White to Off-White Solid Melting Point: 125-129 degrees C Solubility: Acetone, Chloroform, DMSO, Ether, Ethanol, Ethyl Acetate, Methanol
Catalogue number: 012054
Size: 50mg
Form: White to Off-White Solid
Alternative names: Advagraf; FR 900506; Fujimycin; L 679934; Prograf; Protopic; TacroBell; Tacrolimus; Tsukubaenolide
References: Asano, K., et al.: In Vivo, 10, 537 (1996), McCall, E., et al.: Circ. Res., 79, 1110 (1996), Raufman, J.P., et al.: J. Biol. Chem., 271, 19877 (1996), Rokaw, M.D., et al.: Am. J. Physiol., 271, C194 (1996), Knoll, G.A., and Bell, R.C.: Brit. Med. J., 318, 1104 (1999),

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