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FKHR (Forkhead Box Protein O1, Forkhead Box Protein O1A, Forkhead In Rhabdomyosarcoma, FOXO1A, FOXO1)

FKHR (Forkhead Box Protein O1, Forkhead Box Protein O1A, Forkhead In Rhabdomyosarcoma, FOXO1A, FOXO1)

Cat no: F4523-01H

Supplier: United States Biological
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FOXO1A is a 655aa protein belonging to the forkhead family of transcription activators which is characterized by a distinct forkhead domain. The specific function of this protein has not yet been determined, however, it may play a role in myogenic growth and differentiation. It is also known to have a tumor suppressor function by inhibiting cell proliferation and survival. When fused to PAX3 it is known to cause alveolar rhabdomyosarcoma. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.05-0.5ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human ovary Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F4523-01H
Reactivities: Human, Mouse, Rat, Bovine, Canine, Non-Human Primate
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Davis, RJ. et al. Proc. Nat. Acad. Sci. 94:8047-8051 (1997). 2. Huang, H. et al. Science. 314:294-297 (2006).
Additional info: Recognizes human FOXO1A. Species Crossreactivity: chimpanzee, bovine, canine, monkey, mouse, rat. Species sequence homology: pufferfish, chicken, opossum.

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