Quick Search
Products Flt3 (Fms-like Tyrosine Kinase 3, FLT-3, CD135, FL Cytokine Receptor, FLK2, Fms-related Tyrosine Kinase 3, Stem Cell Tyrosine Kinase 1, STK1, STK-1, Tyrosine-protein Kinase Receptor FLT3)
| Catalogue number: | F4600-06 |
| Reactivities: | Human |
| Hosts: | Rabbit |
| Applications: | Immunohistochemistry |
| Size: | 50ug |
| Form: | Supplied as a liquid in PBS, pH 7.7, 0.1% sodium azide. |
| P type: | Pab |
| Isotype: | IgG |
| Purity: | Purified by immunoaffinity chromatography. |
| Alternative names: | EC=2.7.10.1 |
| References: | 1. Clin Adv Hematol Oncol 2004 Nov. 2:708-10 FLT3 Inhibitors in the Treatment of AML. Gilliland DG. 2. Br J Haematol 2005 Sep. 130:726-8 Acute myeloid leukaemia with FLT3 gene mutations of both internal tandem duplication and point mutation type. Chen W, Jones D, Medeiros LJ, Luthra R, and Lin P. 3. Eur J Haematol 2005 Sep. 75:185-92 Delineation and molecular characterization of acute myeloid leukemia patients with coduplication of FLT3 and MLL. Olesen LH, Nyvold CG, Aggerholm A, Nørgaard JM, Guldberg P, and Hokland P. 4. Cancer Res 2005 Aug. 65:7338-47 The FLT3 Internal Tandem Duplication Mutation Prevents Apoptosis in Interleukin-3-Deprived BaF3 Cells Due to Protein Kinase A and Ribosomal S6 Kinase 1-Mediated BAD Phosphorylation at Serine 112. Yang X, Liu L, Sternberg D, Tang L, Galinsky I, Deangelo D, and Stone R. 5. Br J Haematol 2005 Aug. 130:428-36 AML1B transcriptional repressor function is impaired by the Flt3-internal tandem duplication. Takahashi S, Harigae H, Kameoka J, Sasaki T, and Kaku M. |
| Additional info: | Recognizes human FLT3. |
Get the Best Promotions
