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Fluprostenol EIA Kit

Cat no: 516761

Fluprostenol EIA Kit

Fluprostenol is a metabolically stable analog of PGF2(alpha) with potent FP receptor agonist activity. The isopropyl ester of fluprostenol has been approved for use as an ocular hypotensive drug for the treatment of glaucoma and is sold under the Alcon trade name Travoprost. Acting as a prodrug, Fluprostenol isopropyl ester is converted by esterase activity in the cornea to yield the corresponding active free acid, (+)-fluprostenol. Cayman's Fluprostenol EIA is a sensitive detection method for measuring the free acid form of fluprostenol. The assay also detects the isopropyl ester form of fluprostenol, but with less sensitivity. The assay has been validated for use in aqueous humor samples.

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SPECIFICATIONS

Catalog Number

516761

Form

96 Well

P Type

Assay Kits|Prostaglandins|Eicosanoids

Weight

0

Storage Temp

-20

Shipping Temp

-20

Additional Info

Fluprostenol is a metabolically stable analog of PGF2.alpha. with potent FP receptor agonist activity. The isopropyl ester of fluprostenol has recently been approved for use as an ocular hypotensive drug for the treatment of glaucoma and is sold under the Alcon trade name Travoprost. Acting as a prodrug, Fluprostenol isopropyl ester is converted by esterase activity in the cornea to yield the corresponding active free acid, (+)-fluprostenol. Fluprostenol is also used in the veterinary field for the induction of estrus in livestock. Cayman's Fluprostenol EIA is a sensitive detection method for measuring the free acid form of fluprostenol. The assay also detects the isopropyl ester form of fluprostenol, but with less sensitivity. Samples containing a mixture of the isopropyl ester and free acid should be purified and the compounds separated prior to analysis. The assay has been validated for use in aqueous humor samples.

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