FosB, Recombinant, Human (aa113-151)

Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos- B include Fra-1 and Fra-2 genes. This peptide is comprised of aa113-151 with a GST tag.\n\nApplications:\n

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SPECIFICATIONS

Catalog Number

F6042-04

Size

2ug

Form

Supplied as a liquid in 50mM Tris-acetate, pH 7.5, 1mM EDTA and 20% glycerol.

Purity

On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 32kD

References

1. Impaired ventilatory acclimatization to hypoxia in mice lacking the immediate early gene fos B.\n\nRespir Physiol Neurobiol 2005 Jan 15;145(1):23-31\n\n2. The localization of Fos B, a member of transcription factor AP-1 family, in rat odontoblasts and pulpal undifferentiated ectomesenchymal cells.\n\nFolia Histochem Cytobiol 2004;42(3):191-3\n\n3. Fos-B expression is required for polyamine-induced increase in nuclear activator protein-1 DNA binding in discrete structures of murine brain.\n\nJ Neurosci Res 2003 Oct 15;74(2):199-209\n\n4. Expression of c-Fos, Fos B, Jun B, and Zif268 transcription factor proteins in rat barrel cortex following apomorphine-evoked whisking behavior.\n\nNeuroscience 2001;106(4):679-88\n\n5. Sleep and wakefulness in c-fos and fos B gene knockout mice.\n\nBrain Res Mol Brain Res 2000 Aug 14;80(1):75-87\n\n6. The temporal course of expression of c-Fos and Fos B within the medial preoptic area and other brain regions of postpartum female rats during prolonged mother--young interactions.\n\nBehav Neurosci 2000 Jun;114(3):609-22