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FOXA2, CT (Hepatocyte Nuclear Factor 3-beta, HNF-3-beta, HNF-3B, Forkhead Box Protein A2, Transcription Factor 3B, TCF-3B, HNF3B, TCF3B)

Cat no: F9045-10B


Supplier: United States Biological
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The transcription factor Foxa2 (also called hepatocyte nuclear factor 3beta, [HNF-3beta) is implicated in blood glucose homeostasis. Overexpression of Foxa2 decrease heptocyte glycogen levels and reduce expression of glucoe homeostasis genes. The loss of Foxa2 function leads to up-regulation of hexokinase (HK) I and II and glucokinase (HK-IV) mRNA expression. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:2000 Western Blot: 1-3ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F9045-10B
Reactivities: Human
Hosts: Goat
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human FOXA2. Species sequence homology: Mouse, rat.

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