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FOXP2 (Forkhead Box P2, Forkhead Box Protein P2, CAG Repeat Protein 44, CAGH44, SPCH1, Trinucleotide Repeat-containing Gene 10 Protein, TNRC10)

Cat no: F9050-02J

FOXP2 (Forkhead Box P2, Forkhead Box Protein P2, CAG Repeat Protein 44, CAGH44, SPCH1, Trinucleotide Repeat-containing Gene 10 Protein, TNRC10)

FOXP2, otherwise known as Forkhead box P2, a highly conserved member of the FOX family of transcription factors, which plays an essential role in brain and lung development. Studies have revealed the importance of FOXP2 in mediating the development of speech and language, and mutations in the human FOXP2 gene have been linked to developmental verbal dyspraxia.\n\nApplications:\nSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:64,000\nWestern Blot: 0.3-1ug/ml, observed in human brain, cerebellum and frontal cortex lysates and in rat brain lysates on ~85kD bands\nImmunohistochemistry (Paraffin): 2-4ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

F9050-02J

Size

100ug

Applications

ELISA, IHC, WB

Hosts

Goat

Reactivities

Hum, Mouse, Rat, Bov, Can, Prc

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

References

1. Lai CS, Fisher SE, Hurst JA, Vargha-Khadem F, Monaco AP. A forkhead-domain gene is mutated in a severe speech and language disorder. Nature 2001 Oct 4;413(6855):519-23.

Additional Info

Recognizes human FOXP2. Species Crossreactivity: Rat. Species sequence homology: Bovine, canine, feline, mouse and porcine.

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