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Products FP Receptor Polyclonal Antibody
| Catalogue number: | 101802 |
| Hosts: | Rabbit |
| Applications: | Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | mouse FP receptor amino acids 2-16 (SMNSSKQPVSPAAGL){3161} |
| P type: | Antibodies|Eicosanoids |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | The prostaglandin F2.alpha. receptor (FP receptor) is a G protein-coupled receptor known to elicit smooth muscle contraction in a variety of tissues. FP receptor mRNA is found in reproductive, gastric, neural, and ocular tissues as well as specialized cells of the kidney. Two FP receptor isoforms, FPA and FPB have been identified in sheep. FPB receptor is truncated at the carboxy-terminus thereby preventing desensitization (which normally occurs by protein kinase C phosphorylation of FPA) and produces aberrant signalling in FPB transfectants. The existence of a truncated human FP isoform responsible for signal-amplification contributing to luteolysis, cell growth, or malignant transformation is currently unknown. |
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