Fractalkine is a CX3CL chemokine that signals through the CX3CR1 receptor. Fractalkine has been shown to chemoattract monocytes, microglia cells and NK cells. Recombinant rat Fractalkine is an 8.7kD protein containing 76aa, including the four conserved cysteine residues present in CC chemokines.
Source:
Recombinant protein corresponding to rat Fractalkine, expressed in E.coli.
Biological Activity:
Determined by its ability to chemoattract human monocytes using a concentration range of 5-10ng/ml.
Endotoxin:
<0.1ng/ug (1EU/ug)
AA Sequence:
QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQT AALTRNG
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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