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G Protein Coupled Receptor 3 (G-protein Coupled Receptor 3, GPR3, ACCA Orphan Receptor, ACCA)

G Protein Coupled Receptor 3 (G-protein Coupled Receptor 3, GPR3, ACCA Orphan Receptor, ACCA)

Cat no: G8600-06M

Supplier: United States Biological
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GPR3 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle and is crucial for the regulation of meiosis. Mice deficient in GPR3 exhibit premature ovarian failure due to early oocyte aging (Ledent et al. 2005). GPR3 has been reported at low abundance predominantly in the central nervous system and in the lung and kidney (Iismaa et al., 1994). ESTs have been isolated from brain and colon libraries. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 6ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Mouse brain, neurons and glia Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G8600-06M
Reactivities: Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: G Protein-coupled Receptor 3
Additional info: Recognizes mouse GPR3. Species Crossreactivity: rat.

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