Home  >  Products  >  G3BP-1, phosphorylated (Ser232) (Ras GTPase-Activating Protein-Binding Protein 1, GAP SH3 Domain-Binding Protein 1, ATP-dependent DNA helicase VIII, HDH-VIII, G3BP1, G3BP)
G3BP-1, phosphorylated (Ser232) (Ras GTPase-Activating Protein-Binding Protein 1, GAP SH3 Domain-Binding Protein 1, ATP-dependent DNA helicase VIII, HDH-VIII, G3BP1, G3BP)

G3BP-1, phosphorylated (Ser232) (Ras GTPase-Activating Protein-Binding Protein 1, GAP SH3 Domain-Binding Protein 1, ATP-dependent DNA helicase VIII, HDH-VIII, G3BP1, G3BP)

Cat no: G0875-01E

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
G3BP are scaffolding proteins linking signal transduction to RNA metabolismand belongs to a evolutionarily conversed family throughout eukaryota. G3BP exists in three isoforms G3BP1, 2a and 2b which are the products of two distinct genes. The proteins are relatively ubiquitously expressed. G3BP1 plays an potential role in cell cycle regulation. G3BP1 also bind and regulate cmyc which is an important transcription factorpredominantly involved in the regulation of cell cycle progression. The protein acts as a major DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA:DNA and RNA:RNA duplexes in an ATP-dependent fashion. Over-expression of G3BP1 has been observed in a range of human tumors, including breast, head and neck, colon and thyroid. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 Immunohistochemistry (paraffin): 1:50-1:100 Optimal dilutions to be determined by the researcher. Positive Control: 293 cells Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: G0875-01E
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Katharine, I. et al. Int. J. Dev. Biol. 48:1065-1077 (2004).
Additional info: Recognizes human G3BP-1, phosphorylated at Ser232.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave