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Galectin-1, Recombinant, Human (GAL1, LGALS1, GAL-1, Lectin galactoside-binding soluble 1, Beta-galactoside- binding lectin L-14-I, Lactose-binding lectin 1, S-Lac lectin 1, Galaptin, 14kD lectin, HPL, HBL, Putative MAPK-activating protein PM12, GBP, DKFZ

Cat no: G1044-47B

Galectin-1, Recombinant, Human (GAL1, LGALS1, GAL-1, Lectin galactoside-binding soluble 1, Beta-galactoside- binding lectin L-14-I, Lactose-binding lectin 1, S-Lac lectin 1, Galaptin, 14kD lectin, HPL, HBL, Putative MAPK-activating protein PM12, GBP, DKFZ

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 is an autocrine negative growth factor that regulates cell proliferation. Galectin-1 regulates cell apoptosis and cell differentiation. Galectin-1 binds CD45, CD3 and CD4 & inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of lyn kinase. Galectin-1 and its ligands are one of the master regulators of immune responses as T-cell homeostasis and survival, T-cell immune disorders, inflammation and allergies as well as host

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SPECIFICATIONS

Catalog Number

G1044-47B

Size

10ug

Applications

ELISA

Form

Supplied as a lyophilized powder from 10mM sodium phosphate buffer, pH-7.5. Reconstitute with sterile ddH2O, 0.1HSA or BSA to (same/more than)100ug/ml, which can then be further diluted to other aqueous solution

Purity

Chromatographically purified ~95% by SDS-PAGE, RP-HPLC.

References

General References:\n1. Camby, I. et al. (2006) Galectin1:

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