gamma Glutamyl transferase (gGT) from the human kidney is a membrane bound enzyme that transfers the g-glutamyl moiety of g-glutamyl compounds such as glutathione to an acceptor, which may be an aa or a di- or tripeptide or water. The principal functions of gGT may be hydrolysis and metabolism of glutathione. Various human gGT isoforms have been found. The molecular mass of gGT for normal kidney is 90kD and gGT can be used as a renal cell marker.
Applications:
Suitable for use in Western Blot, Immunoprecipitation and Flow Cytometry. Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Positive Control:
CaKi renal tumor cells, renal cell carcinoma, kidney
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.