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Gap-43 (Phospho-Ser41) Polyclonal Antibody

Cat no: 10009400

Gap-43 (Phospho-Ser41) Polyclonal Antibody

Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Ser41 of Gap-43 . Host: rabbit . Cross Reactivity: (+) rat Gap-43; expected to react with bovine, canine, chicken, finch, human, mouse, non-human primates, Xenopus, and zebrafish Gap-43 . Application: WB

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SPECIFICATIONS

Catalog Number

10009400

Applications

WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies

Weight

0

Antigen

phosphopeptide corresponding to amino acid residues surrounding phospho-Ser41 of Gap-43

Storage Temp

-20

Shipping Temp

-20

Additional Info

Gap-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that Gap-43 serves to amplify path finding signals from the growth cone. Gap-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by protein kinase C (Catalog No. 1609-PKC) modulates the interaction of Gap-43 with actin and may also affect neurotransmitter release during forms of plasticity like LTP.

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