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GCN2, phosphorylated (T899) (General Control Non-derepressible 2-like Protein, eIF2a Kinase 4, EIF2AK4)

Cat no: 145473

GCN2, phosphorylated (T899) (General Control Non-derepressible 2-like Protein, eIF2a Kinase 4, EIF2AK4)

GCN2 (General Control Non-derepressible 2-like protein; also eIF2a kinase 4) is a 190-200kD member of the GCN2 subfamily, Ser/Thr kinase family, protein kinase superfamily of proteins It is widely expressed, being found in skeletal muscle cells, fibroblasts, hepatocytes and neurons. GCN2 is a key regulator of metabolism under nutrient deprivation. In particular, when essential amino acids (aa) are limiting, tRNAs exist that are unbound to amino acids. These

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SPECIFICATIONS

Catalog Number

145473

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a lyophilized powder in PBS, Trehalose. Reconstitute in sterile PBS.

P Type

Pab

Purity

Purified by Protein A or G affinity chromatography.

Isotype

IgG

Additional Info

Recognizes human GCN2 when phosphorylated at T899 in Western blots.

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