Home  >  Products  >  GCP 2 (Granulocyte Chemotactic Protein 2, GCP-2, Chemokine (C-X-C Motif) Ligand 6, C-X-C Motif Chemokine 6, CXCL6, Chemokine alpha 3, CKA-3, Small Inducible Cytokine Subfamily B (Cys X Cys) Member 6, SCYB6)

GCP 2 (Granulocyte Chemotactic Protein 2, GCP-2, Chemokine (C-X-C Motif) Ligand 6, C-X-C Motif Chemokine 6, CXCL6, Chemokine alpha 3, CKA-3, Small Inducible Cytokine Subfamily B (Cys X Cys) Member 6, SCYB6)

Cat no: G2023-50B


Supplier: United States Biological
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Human GCP 2 (Granulocyte Chemotactic Protein 2, GCP-2, Chemokine (C-X-C Motif) Ligand 6, C-X-C Motif Chemokine 6, CXCL6, Chemokine alpha 3, CKA-3, Small Inducible Cytokine Subfamily B (Cys X Cys) Member 6, SCYB6) a 7.8-8.8kD connective tissue derived CXC chemokine with several isoforms, which acts as a selective chemoattractant for neutrophils and is closely related to epithelial cell-derived neutrophil-activating peptide-78 (ENA-78/CXCL5). Like IL-8 (CXCL8/GCP-1), GCP-2 was first isolated from osteosarcoma cells, contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors. Applications: Suitable for use in ELISA, Functional Assays, and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.5-2ug/ml Western Blot: 0.1-0.2ug/ml Functional Assays: 2-5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C for short-term only.Stable for 12 months at -20 degrees C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: G2023-50B
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder from PBS, pH 7.2. No preservative added. Reconstitute with 100ul sterile 40-50% glycerol, ddH2O.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Small-inducible Cytokine B6 N-processed Variant 1, Small-inducible Cytokine B6 N-processed Variant 2, Small-inducible Cytokine B6 N-processed Variant 3
References: 1. Proost, P. et al. (1993) Human and bovine granulocyte chemotactic protein-2: complete amino acid sequence and functional characterization as chemokines. Biochem. 32: 10170-10177. 2. Rovai, L.E. et al. (1997) Cloning and characterization of the human granulocyte chemotactic protein-2 gene. J. Immunol. 158: 5257-5266.
Additional info: Recognizes human GCP-2.

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