GINS4, Recombinant, Human, aa1-223, His-Tag (DNA Replication Complex GINS Protein SLD5, SLD5, GINS Complex Subunit 4)

Supplier:

United States Biological

Cat no: 138653

GINS4, Recombinant, Human, aa1-223, His-Tag (DNA Replication Complex GINS Protein SLD5, SLD5, GINS Complex Subunit 4)

GINS4 plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA. \n\nSource:\nRecombinant protein corresponding to aa1-223 from human GINS4 at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~28.2kD (243aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MTEEVDFLGQ DSDGGSEEVV LTPAELIERL EQAWMNEKFA PELLESKPEI VECVMEQLEH MEENLRRAKR EDLKVSIHQM EMERIRYVLS SYLRCRLMKI EKFFPHVLEK EKTRPEGEPS SLSPEELAFA REFMANTESY LKNVALKHMP PNLQKVDLFR AVPKPDLDSY VFLRVRERQE NILVEPDTDE QRDYVIDLEK GSQHLIRYKT IAPLVASGAV QLI\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138653

Size

20ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.2M sodium chloride, 1mM DTT, 20% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Kamada K., et al. (2007) Nat. Struct. Mol. Biol. 14:388-396 2. Chang Y.P., et al. (2007) Proc. Natl. Acad. Sci. U.S.A. 104:12685-12690.

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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