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Glutathione Peroxidase 6 (GPX6, GPx-6, GSHPx-6, GPX5p, GPXP3)

Cat no: G8127-16B

Glutathione Peroxidase 6 (GPX6, GPx-6, GSHPx-6, GPX5p, GPXP3)

PRDX6 is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.\n\nApplications:\nSuitable for use in ELISA. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:64,000\nOptimal dilutions to be determined by the researcher.\n\nPositive Control:\nLysates of cell lines HepG2 and HeLa\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

G8127-16B

Size

100ug

Applications

ELISA

Hosts

Goat

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Richard MJ, Guiraud P, Didier C, Seve M, Flores SC, Favier A. Human immunodeficiency virus type 1 Tat protein impairs selenoglutathione peroxidase expression and activity by a mechanism independent of cellular selenium uptake: consequences on cellular resistance to UV-A radiation. Arch Biochem Biophys. 2001 Feb 15;386(2):213-20. PMID: 11368344.

Additional Info

Recognizes GPX6. Species sequence homology: human.

Alternative Names

Glutathione Peroxidase 6 (Olfactory), dJ1186N24, dJ1186N24.1, EC=1.11.1.9

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