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Goat Anti-COX-2 (human) Affinity-Purified Polyclonal Antibody

Goat Anti-COX-2 (human) Affinity-Purified Polyclonal Antibody

Cat no: 100034


Supplier: Cayman Chemical Company
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Antigen: human COX-2 amino acids 578-596 . Host: goat . Cross-Reactivity: (+) human, ovine, mouse, rat COX-2; (-) COX-1 (all species) . Application(s): WB, ICC, and IHC (formalin-fixed paraffin-embedded sections) . Expression of COX-2, the inducible form of COX, is regulated by growth factor tumors, tumor promoters, bacterial endotoxin, and cytokines
Catalogue number: 100034
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Weight: 0
Form: 1 ea
Antigen: human COX-2 amino acids 578-596
P type: Antibodies|Cyclooxygenase
Shipping temp: -20
Storage temp: -20
Additional info: Cyclooxygenase (COX) catalyzes the first step in the biosynthesis of prostaglandins (PGs), thromboxanes, and prostacyclins: the conversion of arachidonic acid to PGH2. Discoveries of the induction of COX by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothesis that the inducible form of COX, COX-2, is responsible for the biosynthesis of PGs under acute inflammatory conditions. COX-2 is a 72 kDa protein which has been cloned from a variety of species including human, mouse, rat, and ovine.

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