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GPR17 (C-Term) Polyclonal Antibody

Cat no: 10136

GPR17 (C-Term) Polyclonal Antibody

Antigen: human GPR17 amino acids 351-367 . Host: rabbit . Cross Reactivity: (+) human, mouse, and rat GPR17 . Application(s): FC, ICC, and WB . GPR17 is a GPCR that recognizes signals from both nucleotides and CysLTs. GPR17 is upregulated upon ischemic injury, and its inhibition has been shown to decrease ischemic damage.

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SPECIFICATIONS

Catalog Number

10136

Applications

FC, ICC, WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies

Weight

0

Antigen

human GPR17 amino acids 351-367 (SFEGKTNESSLSAKSEL)

Storage Temp

-20

Shipping Temp

-20

Additional Info

GPR17 is a G protein-coupled receptor that has been identified as a dualistic receptor recognizing signals from two unrelated chemical families: nucleotides and CysLTs. The deorphanization of GPR17 supports the suggested crosstalk between nucleotides and CysLTs during inflammation and injury. mRNA transcripts encoding this transmembrane receptor are most strongly expressed in the brain, kidney, and heart. Upon ischemic injury, GPR17 is upregulated in these tissues and its inhibition has been shown to decrease ischemic damage. This finding suggests GPR17 as a pharmacological target of ischemic injury. Cayman

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