Catalogue number: | 14083 |
Hosts: | Rabbit |
Applications: | ELISA, Immunocytochemistry, Western Blot |
Weight: | 0 |
Form: | 1 ea |
Antigen: | human GPR31 amino acids 288-298 |
P type: | Antibodies |
Shipping temp: | -20 |
Storage temp: | -20 |
Additional info: | GPR31 is a 319 amino acid G protein-coupled receptor (GPCR) that acts as the receptor for the arachidonic acid metabolite 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12(S)-HETE) (Item No. 34570). Binding of 12(S)-HETE to GPR31 leads to the activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kB pathways. The dysregulation of GPR31 has been implicated in diseases such as arthritis, Alzheimer |