

Supplier:
Cayman Chemical CompanyCat no: 15727
GPR43 (Internal) Polyclonal Antibody
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SPECIFICATIONS
Catalog Number
15727
Applications
FC, IF, WB
Hosts
Rabbit
Form
1 ea
P Type
Antibodies|Fatty Acid Binding Proteins|Intracellular Signaling|Lipid Mediators
Weight
0
Antigen
peptide from the internal region of human GPR43
Storage Temp
-20
Shipping Temp
-20
Additional Info
GPR43 is a G protein-coupled receptor activated by short chain fatty acids (SCFAs). Several SCFAs have the potential to bind and activate GPR43, including acetate, formate, propionate, and butyrate. GPR43 couples through the Pertussis toxin-sensitive Gi/o and the pertussis toxin-insensitive Gq protein families and its expression has been described in enteroendocrine cells and neutrophils. The activation of GPR43 induces an increase in intracellular Ca2+, ERK1/2 activation, and a decrease in intracellular cAMP. Activation of GPR43 may be involved in intestinal inflammation. The predicted size of GPR43 is 37 kDa. Cayman
Applications
ELISA, IF, IP, WB
Hosts
Rabbit
Applications
ELISA, IP, WB
Hosts
Rabbit
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