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Products GPR43 (Internal) Polyclonal Antibody
| Catalogue number: | 15727 |
| Hosts: | Rabbit |
| Applications: | Flow Cytometry, Immunofluorescence, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | peptide from the internal region of human GPR43 |
| P type: | Antibodies|Fatty Acid Binding Proteins|Intracellular Signaling|Lipid Mediators |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | GPR43 is a G protein-coupled receptor activated by short chain fatty acids (SCFAs). Several SCFAs have the potential to bind and activate GPR43, including acetate, formate, propionate, and butyrate. GPR43 couples through the Pertussis toxin-sensitive Gi/o and the pertussis toxin-insensitive Gq protein families and its expression has been described in enteroendocrine cells and neutrophils. The activation of GPR43 induces an increase in intracellular Ca2+, ERK1/2 activation, and a decrease in intracellular cAMP. Activation of GPR43 may be involved in intestinal inflammation. The predicted size of GPR43 is 37 kDa. Cayman |
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