Catalogue number: | 10009374 |
Hosts: | Rabbit |
Applications: | Western Blot |
Weight: | 0 |
Form: | 1 ea |
Antigen: | phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser9 of GSK-3(beta) |
P type: | Antibodies|Intracellular Signaling |
Shipping temp: | -20 |
Storage temp: | -20 |
Additional info: | Glycogen synthase kinase 3 (GSK-3) is a serine/threonine kinase that is involved in the regulation of many signaling pathways. To date, two isoforms have been identified: GSK-3(alpha) and GSK-3(beta). Specifically, GSK-3(beta) has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways. It has been suggested that Ser9 phosphorylation underlies the inhibition of GSK-3(beta) by insulin. |