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GSTM4, Recombinant, Human (Glutathione S-transferase Mu 4 Isoform 1, GST Class-mu 4, GST-Mu2, GSTM4-4)

Cat no: G8134-25H

GSTM4, Recombinant, Human (Glutathione S-transferase Mu 4 Isoform 1, GST Class-mu 4, GST-Mu2, GSTM4-4)

Glutathione S-transferase Mu 4 isoform 1, also known as GSTM4, is member of the glutathione s-transferase (GST) family of proteins. There are eight families of GST proteins, namely alpha, kappa, mu, omega, pi, sigma, theta and zeta, each of which is composed of proteins that have a variety of functions throughout the cell. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.\n\nSource:\nRecombinant corresponding to aa1-218 of human GSTM4 protein, fused to His-tag at N-terminus, expressed in E.coli.\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MSMTLGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGAHKI TQSNAILCYI ARKHNLCGET EEEKIRVDIL ENQAMDVSNQ LARVCYSPDF EKLKPEYLEE LPTMMQHFSQ FLGKRPWFVG DKITFVDFLA YDVLDLHRIF EPNCLDAFPN LKDFISRFEG LEKISAYMKS SRFLPKPLYT RVAVWGNK\n\nMolecular Weight: 27.7kD (238aa) confirmed by MALDI-TOF\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

G8134-25H

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 10% glycerol, 50mM sodium chloride.

Purity

~95% (SDS-PAGE).

References

1. Boqaards JJ., et al. (1992) Biochem J. 289(2):383-8. 2. Rozell B., et al. (1992) Xenobiotica. 23(8):835-49.

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