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Guanylate Cyclase (alpha) subunit (soluble) Polyclonal Antibody

Cat no: 160895

Guanylate Cyclase (alpha) subunit (soluble) Polyclonal Antibody

Antigen: human sGC a1 subunit amino acids 418-436 . Host: rabbit . Cross Reactivity: (+) human, bovine, and mouse sGC a1 subunit . Application(s): WB . Soluble guanylate cyclase is a heterodimeric enzyme, composed of (alpha) and (beta) subunits, that synthesizes cGMP from GTP. The enzyme is activated by the binding of nitric oxide or carbon monoxide to the heme group of the enzyme.

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SPECIFICATIONS

Catalog Number

160895

Applications

WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies|Intracellular Signaling

Weight

0

Antigen

human sGC a1 subunit amino acids 418-436 (EQARAQDGLKKRLGKLKAT)

Storage Temp

-20

Shipping Temp

-20

Additional Info

Soluble guanylate cyclase is a heterodimeric enzyme, composed of .alpha. and .beta. subunits, that synthesizes cGMP from GTP. The enzyme is activated by the binding of nitric oxide or carbon monoxide to the heme group of the enzyme. Chronic hypoxia upregulates soluble guanylate expression in rat lung. The .alpha.1 subunit contains 690-717 amino acids and has a molecular mass of 77-82 kDa. The cloned .beta.1 subunit of guanylate cyclase from human, bovine, and rat sources contains 619 amino acids and has a molecular mass of approximately 70,000.

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