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Guanylate Cyclase (beta)1 subunit (soluble) Polyclonal Antibody

Cat no: 160897

Guanylate Cyclase (beta)1 subunit (soluble) Polyclonal Antibody

Antigen: rat soluble guanylate cyclase (beta)1 subunit amino acids 188-207 . Host: rabbit . Cross Reactivity: (+) human, bovine, and rat soluble guanylate cyclase (beta)1 subunit; (-) (alpha)1 subunit . Application(s): IHC and WB . Soluble guanylate cyclase is a heterodimeric enzyme, composed of (alpha) and (beta) subunits, that synthesizes cGMP from GTP. The enzyme is activated by the binding of nitric oxide or carbon monoxide to the heme group of the enzyme.

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SPECIFICATIONS

Catalog Number

160897

Applications

IHC, WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies|Intracellular Signaling

Weight

0

Antigen

rat soluble guanylate cyclase (beta)1 subunit amino acids 188-207 (EDFYEDLDRFEENGTQDSR; last D=E in human and bovine){3531,4654,3535}

Storage Temp

-20

Shipping Temp

-20

Additional Info

Soluble guanylate cyclase is a heterodimeric enzyme, composed of a and b subunits, that catalyzes the synthesis of cGMP from GTP. The enzyme is activated by the binding of nitric oxide to the heme group of the enzyme. The cloned b1 subunit of guanylate cyclase from human, bovine, and rat sources contains 619 amino acids and has a molecular mass of approximately 70,000. The a1 subunit contains 690-717 amino acids and has a molecular mass of 77-82 kDa. This antibody will specifically recognize only the b1 subunit of soluble guanylate cyclase.

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