H5N1-M2 Antibody

Cat no: 250681

Supplier: ABBIOTEC

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Description
Additional Information

Avian influenza Matri, Xenopus/Amphibian, Protein-2 (H5N1-M2) forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influ, Xenopus/Amphibian, of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP),Mouse,atri, Xenopus/Amphibian, protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. The M2 protein from most influenza A strains is inhibited by amantadine and rimantadine, resulting in viral uncoating incapacity.

Catalogue number:	250681
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	O70632
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of influenza A virus matri, Xenopus/Amphibian, protein 2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Avian influenza Matri, Xenopus/Amphibian, Protein-2; Matri, Xenopus/Amphibian, protein 2; Proton channel protein M2; H5N1; H5N1-M2; Influenza A virus