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HDAC8, phosphorylated (Ser39) (Histone Deacetylase 8, Histone Deacetylase-like 1, HDACL1, CDA07, HD8)

Cat no: H1827-56F3

HDAC8, phosphorylated (Ser39) (Histone Deacetylase 8, Histone Deacetylase-like 1, HDACL1, CDA07, HD8)

Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from an E-N-acetyl lysine amino acid on a histone or other proteins. Its action is opposite to that of histone acetyltransferase. HDAC proteins are found in three groups, the first two groups belong to the classical HDACs and their activities are inhibited by trichostatin A (TSA) whereas the third group is a family of NAD+-dependent proteins not affected by TSA. Homologues to all three groups are found in yeast having the names reduced potassium dependency 3 (Rpd3) - corresponds to class 1, histone deacetylase 1 (hda1) - to class 2 and silent information regulator 2(Sir2) - class3 Affinity purified rabbit polyclonal anti-HDAC 8 antibody is developed with c-terminal peptide of human histone deacetylase 8. It could be used for detection and isolation of HDAC 8.\n\nApplications:\nSuitable for use in Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry: 1:50-1:100 \nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

H1827-56F3

Size

50ug

Applications

IHC

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

Additional Info

Recognizes human HDAC8 when phosphorylated at serine 39. Species Cross-Reactivity: mouse, rat.

Read more on Supplier website

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info
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