Home  >  Products  >  HDDC3, Recombinant, Human, aa1-140 His-tag (Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1, HD Domain-containing Protein 3, Metazoan SpoT Homolog 1, MESH1, Penta-phosphate Guanosine-3'-pyrophosphohydrolase, (ppGpp)ase, MESH1)
HDDC3, Recombinant, Human, aa1-140 His-tag (Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1, HD Domain-containing Protein 3, Metazoan SpoT Homolog 1, MESH1, Penta-phosphate Guanosine-3'-pyrophosphohydrolase, (ppGpp)ase, MESH1)

HDDC3, Recombinant, Human, aa1-140 His-tag (Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1, HD Domain-containing Protein 3, Metazoan SpoT Homolog 1, MESH1, Penta-phosphate Guanosine-3'-pyrophosphohydrolase, (ppGpp)ase, MESH1)

Cat no: 029660

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
HDDC3, contains an active site for ppGpp hydrolysis and a conserved His-Asp-box motif for Mn(2+) binding. Consistent with these structural data, HDDC3 efficiently catalyzes hydrolysis of guanosine 3',5'-diphosphate (ppGpp) both in vitro and in vivo. HDDC3 also suppresses SpoT-deficient lethality and RelA-induced delayed cell growth in bacteria. Source: Recombinant corresponding to aa1-140 from human HDDC3, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSEAAQLLE AADFAARKHR QQRRKDPEGT PYINHPIGVA RILTHEAGIT DIVVLQAALL HDTVEDTDTT LDEVELHFGA QVRRLVEEVT DDKTLPKLER KRLQVEQAPH SSPGAKLVKL ADKLYNLRDL NRCTPEVKIQ Molecular Weight: ~17.9kD (MALDI-TOF) Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 029660
Size: 100ug
Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 40% glycerol, 0.15M sodium chloride, 1mM DTT.
Purity: ~90% (SDS-PAGE)
References: 1. Sun D., et al. (2010) Nat. Struct. Mol. Biol. 17:1188-1194. 2. Zody M.C., et al. (2006) Nature. 440:671-675.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave