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Heat Shock Protein 60 (60kD Heat Shock Protein, Mitochondrial, 60kD Chaperonin, Chaperonin 60, CPN60, Heat Shock Protein 60, HSP-60, Hsp60, HuCHA60, Mitochondrial Matrix Protein P1, P60 Lymphocyte Protein, HSPD1)

Cat no: H1830-75A

Heat Shock Protein 60 (60kD Heat Shock Protein, Mitochondrial, 60kD Chaperonin, Chaperonin 60, CPN60, Heat Shock Protein 60, HSP-60, Hsp60, HuCHA60, Mitochondrial Matrix Protein P1, P60 Lymphocyte Protein, HSPD1)

A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against bacterial hsp60 and against its mammalian homolog.\n\nApplications:\nSuitable for use in Western Blot, Immunoprecipitation, and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 2-4ug/ml\nImmunohistochemistry (paraffin): 4-8ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with 200ul sterile dH20. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

H1830-75A

Size

100ug

Applications

IHC, IP, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Ch/Bird

Form

Supplied as a lyophilized powder from 1.2% sodium acetate, 2mg BSA, 0.01mg sodium azide. Reconstitute in sterile ddH2O, PBS.

P Type

Mab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG1

Additional Info

Recognizes human HSP60. Species Crossreactivity: chicken, rat.

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