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Heme oxygenase 2, decycling (HMOX2, HO-2, Heme Oxygenase Decyclizing 2)

Cat no: H1847-69J

Heme oxygenase 2, decycling (HMOX2, HO-2, Heme Oxygenase Decyclizing 2)

Heme oxygenase-2 (HO-2) is the constitutive isoform of heme oxygenase which catalyzes the NADPH, O2 and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, iron and biliverdin that is immediately reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator; biliverdin and its product bilirubin are potent antioxidants;

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SPECIFICATIONS

Catalog Number

H1847-69J

Size

100ug

Applications

WB

Hosts

Goat

Reactivities

Hum

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.

P Type

Pab

Purity

Purified by affinity chromatography.

Isotype

IgG

References

1. Sha L, Farrugia G, Harmsen WS, Szurszewski JH. Membrane potential gradient is carbon monoxide-dependent in mouse and human small intestine. American journal of physiology. Gastrointestinal and liver physiology 2007 Aug 293 (2): G438-45. PMID: 17510199.

Additional Info

Recognizes human HMOX2. Sequence Homology: mouse, bovine.

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