Hexosaminidase A, Recombinant, Human, aa89-529, His-Tag (beta-hexosaminidase Subunit Alpha, TSD, HEXA)

Supplier:

United States Biological

Cat no: 138665

Hexosaminidase A, Recombinant, Human, aa89-529, His-Tag (beta-hexosaminidase Subunit Alpha, TSD, HEXA)

HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). \n\nSource:\nRecombinant protein corresponding to aa89-529 from human HEXA at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~52.9kD (464aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSTLEKNVL VVSVVTPGCN QLPTLESVEN YTLTINDDQC LLLSETVWGA LRGLETFSQL VWKSAEGTFF INKTEIEDFP RFPHRGLLLD TSRHYLPLSS ILDTLDVMAY NKLNVFHWHL VDDPSFPYES FTFPELMRKG SYNPVTHIYT AQDVKEVIEY ARLRGIRVLA EFDTPGHTLS WGPGIPGLLT PCYSGSEPSG TFGPVNPSLN NTYEFMSTFF LEVSSVFPDF YLHLGGDEVD FTCWKSNPEI QDFMRKKGFG EDFKQLESFY IQTLLDIVSS YGKGYVVWQE VFDNKVKIQP DTIIQVWRED IPVNYMKELE LVTKAGFRAL LSAPWYLNRI SYGPDWKDFY VVEPLAFEGT PEQKALVIGG EACMWGEYVD NTNLVPRLWP RAGAVAERLW SNKLTSDLTF AYERLSHFRC ELLRRGVQAQ\nPLNVGFCEQE FEQT\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

138665

Size

100ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.4M urea, 10% glycerol.

Purity

~85% (SDS-PAGE)

References

1. Nakano T., et al. (1988) J. Neurochem. 51:984-987.

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

More from
United States Biological

All suplier products

United States Biological

EBI3, Control Peptide (Interleukin-27 Subunit beta, IL-27 Subunit beta, IL-27B, Epstein-Barr Virus-induced Gene 3 Protein, EBV-induced Gene 3 Protein, IL27B)

Applications

ELISA

United States Biological

RNASEH2A, Control Peptide (Ribonuclease H2 Subunit A, RNase H2 Subunit A, Ribonuclease HI Subunit A, Ribonuclease HI Large Subunit, RNase HI Large Subunit, RNase H(35), Aicardi-Goutieres Syndrome 4 Protein, AGS4, RNASEHI, RNHIA)

Applications

ELISA

United States Biological

CRMP1, Control Peptide (Dihydropyrimidinase-related Protein 1, DRP-1, Collapsin Response Mediator Protein 1, CRMP-1, Unc-33-like Phosphoprotein 3, ULIP-3, DPYSL1, ULIP3)

Applications

ELISA

United States Biological

IL16, Control Peptide (IL-16, Pro-interleukin-16, Lymphocyte Chemoattractant Factor, LCF)

Applications

ELISA

United States Biological

OCC1, Control Peptide (Overexpressed in Colon Carcinoma 1 Protein, OCC-1, AGD3, C12orf75, MGC148100, MGC149157)

Applications

ELISA

United States Biological

KLRA1, Control Peptide (Killer Cell Lectin-Like Receptor Subfamily A, Member 1, KLRA#, LY49L, Ly-49L, Ly49, MGC126520, MGC126522)

Applications

ELISA

United States Biological

SLC39A10, Control Peptide (Zinc Transporter ZIP10, Solute Carrier Family 39 Member 10, Zrt- and Irt-like Protein 10, ZIP-10, KIAA1265, ZIP10)

Applications

ELISA

United States Biological

Klra3, Control Peptide (Killer Cell Lectin-like Receptor 3, 5E6, Lymphocyte Antigen 49c, Ly-49c, Nk2.1, T-cell Surface Glycoprotein Ly-49C, Ly-49c, Ly49C, MGC123910)

Applications

ELISA

Advertisehere

BMA Biomedicals Horizontal banner

Latest promotion FROM:

BMA Biomedicals

Latest promotions

Explore all promotions

B-Bridge International, Inc.

DNA Cleanup in 7 Minutes, 10% OFF

Spend less time on DNA cleanup so you can do more science. The MSB Spin PCRapace is the fastest way to purify your DNA from PCR, restriction digestion, and...

BD (Becton, Dickinson and Company)

Analyze your cells with more colors at lower prices!

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

Europa Bioproducts Ltd

20% discount on Bovine Serum Albumin!

As an incentive to qualify our BSA, we are offering a 20% discount when you purchase your first 100g, 500g or 1000g of any grade of Bovine Serum Albumin....

Cecil Instruments Limited

Cecil Spectrophotometer Enhancements for Free!

It is not every day that you are given something for nothing. We are giving away additional spectrophotometer software.Cecil Instruments have enhanced the...

Innovative Research, Inc

Premium US Origin Fetal Bovine Serum for only $95 per 500ml!

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

Advanced Targeting Systems, Inc.

Secondary Conjugates - Save 20%

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

Cayman Chemical Company

Cayman Challenge

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

SDIX

Custom Polyclonal Antibodies

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

Cell Sciences, Inc.

Recombinant Proteins

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Bibby Scientific

73 series spectrophotometer

Jenway’s 73 series spectrophotometer range provides four models with a narrow spectral bandwidth of 5nm and an absorbance range of –0.3 to 2.5A,...

Everest Biotech Ltd

Custom antibody for $300

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...

Top suppliers

Explore all suppliers

United States Biological

230753 products

Carl Zeiss Microscopy

27 products

Promega Corporation

11 products

Panasonic Healthcare Company

5 products

Life Technologies

1 products

Nikon Instruments Europe

11 products

Olympus Europa Holding GmbH

3 products

Leica Microsystems, Inc.

10 products

GE Healthcare Life Sciences

2 products

Tecan Trading AG

19 products

Beckman Coulter, Inc.

1 products

AB SCIEX

3 products

BD (Becton, Dickinson and Company)

1 products

RANDOX TOXICOLOGY

5 products

Randox Food Diagnostics

6 products