

Supplier:
Cayman Chemical CompanyCat no: 10347
HIF-1(alpha) Monoclonal Antibody (Clone H1(alpha)67)
Prices direct from Cayman Chemical Company
Quick response times
Exclusive Biosave savings/discounts
SPECIFICATIONS
Catalog Number
10347
Applications
IHC, WB
Hosts
Mouse
Form
1 ea
P Type
Antibodies|Intracellular Signaling
Weight
0
Antigen
human HIF-1(alpha) amino acids 432-528
Storage Temp
-20
Shipping Temp
-20
Additional Info
Hypoxia inducible factor-1(alpha) (HIF-1(alpha)) is a transcription factor that accumulates under low-oxygen conditions. Following hypoxic stimulus and cytoplasmic accumulation, HIF-1(alpha) migrates to the nucleus where, with other transcription factors, it drives the production of stress-adaptive proteins. This response is essential for maintenance of normal oxidative physiology, however overexpression in cancer cells promotes tumor survival. HIF-1(alpha) is an EPAS-1 family member with phosphorylation dependent activities. HIF-1(alpha) will migrate to the apparent molecular weights of 110-125 kDa (by SDS-PAGE) depending on phosphorylation status. Positive controls include human, primate, and murine cell cultures grown in hypoxic conditions or treated with prolyl hydroxylase inhibitors such as DMOG (Item No. 71210), 2,4-DPD (Item No. 71200), desferrioxamine, or CoCl2.
Applications
ELISA, IF, IP, WB
Hosts
Rabbit
Applications
ELISA, IP, WB
Hosts
Rabbit
Latest promotions
Spend less time on DNA cleanup so you can do more science. The MSB Spin PCRapace is the fastest way to purify your DNA from PCR, restriction digestion, and...
Genovis introduces GlycINATOR™• Works on most IgGs• Effective on high-mannose and bisected N-linked Fc-glycans • Rapid – 30-minute...
Use promo code EASY3 to receive 13% off and FREE shipping!Experience a new dimension of electronic pipetting with the NEW Easypet 3 pipette controller. The...
New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...
As an incentive to qualify our BSA, we are offering a 20% discount when you purchase your first 100g, 500g or 1000g of any grade of Bovine Serum Albumin....
It is not every day that you are given something for nothing. We are giving away additional spectrophotometer software.Cecil Instruments have enhanced the...
We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!
For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...
10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...
Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...
Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...
Jenway’s 73 series spectrophotometer range provides four models with a narrow spectral bandwidth of 5nm and an absorbance range of –0.3 to 2.5A,...
Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...
Top suppliers

Carl Zeiss Microscopy
27 products

Eppendorf
1 products

Promega Corporation
11 products

Panasonic Healthcare Company
5 products

Life Technologies
1 products

Nikon Instruments Europe
11 products

Olympus Europa Holding GmbH
3 products

Leica Microsystems, Inc.
10 products

GE Healthcare Life Sciences
2 products

Tecan Trading AG
19 products

Beckman Coulter, Inc.
1 products

United States Biological
230753 products

AB SCIEX
3 products
BD (Becton, Dickinson and Company)
1 products

RANDOX TOXICOLOGY
5 products

Randox Food Diagnostics
6 products