Histone H2B.c, NT (HIST1H2BL, H2BFC, Histone H2B type 1-L, Histone H2B.c) (Azide free) (HRP)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.\n\nApplications:\nSuitable for use in Western Blot, Flow Cytometry, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\nFlow Cytometry: 1:10-50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze horseradish peroxidase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

036610-HRP

Size

200ul

Applications

ELISA, FC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free). Conjugated to HRP.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Kim, S.C., et al. Mol. Cell 23(4):607-618(2006)\nBeck, H.C., et al. Mol. Cell Proteomics 5(7):1314-1325(2006)\nPavri, R., et al. Cell 125(4):703-717(2006)\nBonenfant, D., et al. Mol. Cell Proteomics 5(3):541-552(2006)\nZhu, B., et al. Mol. Cell 20(4):601-611(2005)

Additional Info

Human

Alternative Names

HIST1H2BL, H2BFC, Histone H2B type 1-L, Histone H2B.c