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HIV-1 gp120, Strain IIIB (Human Immunodeficiency Virus Type 1) (FITC)

Cat no: H6003-34H3

HIV-1 gp120, Strain IIIB (Human Immunodeficiency Virus Type 1) (FITC)

HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response\n\nApplications: \nSuitable for use in Dot Blot, Flow Cytometry, Immunohistochemistry and Immunofluorescence. Other applications not tested.\n\nRecommended Dilution:\nDot Blot: 1:100\nImmunofluorescence (Direct, cell surface): 1:50\nOptimal dilutions to be determined by the researcher.\n\nF/P Ratio: \n2-4 \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

H6003-34H3

Size

50Tests

Applications

FC, IF

Hosts

Rabbit

Form

Supplied as a liquid in Tris, pH 8. No stabilizers or preservatives added. labeled with fluorescein isothiocyanate (FITC).

P Type

Pab

Purity

Purified ((same/more than) 95%) by gel exclusion chromatography.

Isotype

IgG

Additional Info

Recognizes native and recombinant HIV-1 gp120 in Dot Blot assays and stains cell surfaces in direct immunofluorescence assays.

Read more on Supplier website

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info

Applications

FC

Hosts

Mouse

Reactivities

Hum

More info
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