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HMGB1 ELISA

HMGB1 ELISA


HMGB1
is a protein that is normally present in the nucleus and cytoplasm of mammalian cells, and is involved in gene transcription as a chromatin binder. It can then either be released passively as a soluble molecule from necrotic cells, or may be actively secreted from inflammatory cells.

Thus, HMGB1 acts as a cytokine, exhibiting similar pro-inflammatory effects as do TNF- and IL-6. Any disease coping with dying, necrotic cells will therefore be involved with HMGB1 in one of these two cases.

IBL offers the only commercial ELISA worldwide for measuring HMGB1.

Prices direct from IBL International GmbH

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