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Hsp40 Polyclonal Antibody

Cat no: 10011383

Hsp40 Polyclonal Antibody

Antigen: human recombinant Hsp40 . Host: rabbit . Cross-reactivity: (+) human and rat Hsp40 . Application: WB

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SPECIFICATIONS

Catalog Number

10011383

Applications

WB

Hosts

Rabbit

Form

100 microL

P Type

Antibodies|Heat Shock Protein

Purity

40 kDa

Weight

0

Antigen

human recombinant Hsp40{15473}

Storage Temp

-20

Shipping Temp

-20

Additional Info

DnaJ/Hsp40 proteins have been preserved throughout evolution and are important for protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of chaperone proteins, Hsp70s. Because the ATP hydrolysis is essential for the activity of Hsp70s, DnaJ/Hsp40 proteins actually determine the activity of Hsp70s by stabilizing their interaction with substrate proteins. DnaJ/Hsp40 proteins all contain the J domain through which they bind to Hsp70s. Hsp40, also known as HDJ1, is a basic mammalian 40 kDa heat shock protein which is not only homologous to the bacterial heat shock protein (DnaJ), but also yeast DnaJ-related proteins such as SCJ1, Sec63/Npl1, YDJ1, and SIS1. Hsp40 is inducible by stress including heat after which is moves from the cytoplasm to the nucleus and nucleoli; an intracellular pattern similar to Hsc70/Hsp70, the mammalian homologues of the bacterial heat shock protein, DnaK.

SUPPLIER INFO

Cayman Chemical Company

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