Human Antigen peptide transporter 2 (TAP2) ELISA Kit

Cat no: KTE60472

Supplier: Abbkine Scientific Co.Ltd.

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The membrane-associated protein encoded by TAP2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). Antigen peptide transporter 2 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. Antigen peptide transporter 2 is involved in antigen presentation. Antigen peptide transporter 2 forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in TAP2 may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.

Catalogue number:	KTE60472
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	Q03519
Gene:	6891
Additional info:	Human Antigen peptide transporter 2 (TAP2) ELISA Kit has high sensitivity and excellent specificity for detection of Human TAP2. No significant cross-reactivity or interference between Human TAP2 and analogues was observed.

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Human Antigen peptide transporter 2 (TAP2) ELISA Kit

Cat no: KTE60472

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