Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (ACAP1) ELISA Kit

ACAP1 and ACAP2 were recruited to platelet-derived growth factor (PDGF)-induced dorsal membrane ruffles in NIH 3T3 mouse fibroblasts, and overexpression inhibited ruffle formation. The deduced protein contains 740 amino acids and shares 52% sequence identity with CENTB2. highest expression in spleen, thymus, and peripheral blood leukocytes, intermediate expression in lung, testis, and small intestine, and weak expression in prostate, ovary, and colon. No expression was detected in heart, brain, placenta, liver, skeletal muscle, kidney, and pancreas, and no expression was detected in HeLa cells.ACAP1 shares significant similarity with CENTB2, which the authors called ACAP2, and 95% identity with mouse Acap1.

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SPECIFICATIONS

Catalog Number

KTE60873

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

9744

Accession

Q15027

Additional Info

Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (ACAP1) ELISA Kit has high sensitivity and excellent specificity for detection of Human ACAP1. No significant cross-reactivity or interference between Human ACAP1 and analogues was observed.