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Human Cystine/glutamate transporter (SLC7A11) ELISA Kit

Cat no: KTE60588

Human Cystine/glutamate transporter (SLC7A11) ELISA Kit

SLC7A11 is a member of a heteromeric Na(+)-independent anionic amino acid transport system highly specific for cystine and glutamate. In this system, designated system Xc(-), the anionic form of cystine is transported in exchange for glutamate. The deduced 502-amino acid protein had an apparent molecular mass of about 40 kD following in vitro translation in canine pancreatic microsomes. Mouse xCT was found to be extremely hydrophobic and was predicted to contain 12 membrane-spanning domains. Northern blot analysis of activated mouse macrophages detected transcripts of 12, 3.5, and 2.5 kb. Northern blot analysis of mouse tissues detected expression in brain, but not in other organs tested. The 501-amino acid XCT protein has 12 transmembrane domains and cytoplasmic N and C termini.

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SPECIFICATIONS

Catalog Number

KTE60588

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

23657

Accession

Q9UPY5

Additional Info

Human Cystine/glutamate transporter (SLC7A11) ELISA Kit has high sensitivity and excellent specificity for detection of Human SLC7A11. No significant cross-reactivity or interference between Human SLC7A11 and analogues was observed.

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