Platelet membrane glycoprotein IIb/IIIa (GPIIb/IIIa, integrin ?IIb?3) is a member of the integrin family of cell membrane receptors that play key roles in thrombus formation, platelet aggregation, embryogenesis and intercellular adhesion. Each integrin receptor complex consists of a heavy (?) and a light (?) chain associated as a calcium-dependent heterodimer with a molecular mass of 140 kDa and 90 kDa respectively (1). GPIIb/IIIa serves as an inducible receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin (2, 3). The simultaneous occupancy on adjacent platelets of receptors with dimeric fibrinogen molecules leads to platelet aggregation. Hereditary defects of the GPIIb/IIIa receptor cause Glanzmann
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