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Human Matrix metalloproteinase 13 (MMP-13) ELISA Kit

Human Matrix metalloproteinase 13 (MMP-13) ELISA Kit

Cat no: KTE62620

Supplier: Abbkine Scientific Co.Ltd.
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MMP-13 has been proposed to participate in aggrecan degradation associated with osteoarthritis and cleavage of type II collagen in osteoarthritic cartilage explants and in tumor progression and metastasis . In addition, it can cleave type I, III, IV, IX, X and XIV collagens and fibronectin. MMP-13 is likely to play a crucial role in the modulation of extracellular matrix degradation and cell-matrix interactions .MMP-13 is expressed by several metastatic tumors including breast carcinomas, chondrosarcomas, head and neck carcinomas, and in degenerative bone diseases including rheumatoid arthritis. Wild type and mutant p53, a tumor suppressor gene, differentially regulate MMP-13 gene expression . Members of the activator protein-1 and core-binding factor families increase MMP-13 promoter activity in normal, differentiating osteoblasts .
Catalogue number: KTE62620
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P45452
Gene: 4322
Additional info: Human Matrix metalloproteinase 13 (MMP-13) ELISA Kit has high sensitivity and excellent specificity for detection of Human MMP13. No significant cross-reactivity or interference between Human MMP13 and analogues was observed.

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