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Human Polycomb protein SUZ12 (SUZ12) ELISA Kit

Cat no: KTE60407

Human Polycomb protein SUZ12 (SUZ12) ELISA Kit

SUZ12 has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined.Suz12 mutants exhibited very strong homeotic transformations and that Suz12 function is required throughout development to maintain the repressed state of Hox genes in Drosophila. Unlike most other Polycomb group mutations, Suz12 mutations are strong suppressors of position-effect variegation, suggesting that Suz12 also functions in heterochromatin-mediated repression. Furthermore, Suz12 function is required for germ cell development. The SUZ12 protein is highly conserved in vertebrates and is also related to several Arabidopsis proteins.

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SPECIFICATIONS

Catalog Number

KTE60407

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

23512

Accession

Q15022

Additional Info

Human Polycomb protein SUZ12 (SUZ12) ELISA Kit has high sensitivity and excellent specificity for detection of Human SUZ12. No significant cross-reactivity or interference between Human SUZ12 and analogues was observed.

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