Human Pyrin domain-containing protein 2 (PYDC2) ELISA Kit

Cat no: KTE61019

Supplier: Abbkine Scientific Co.Ltd.

0 reviews | Write a Review Pencil

Read More on Supplier Website

Description
Additional Information

Pyrin domain (PYD) proteins have recently emerged as important signaling molecules involved in the development of innate immunity against intracellular pathogens through activation of inflammatory mediator pathways. It is modulated by a cellular PYD-only protein (cPOP1), which binds to ASC and interferes with the recruitment of ASC to activated PYD-NLRs. POP (cPOP2), which shows highest homology to the PYD of PAN1. cPOP2 binds to ASC and PAN1, thereby blocking formation of cryopyrin and PAN1-containing inflammasomes, activation of caspase-1, and subsequent processing and secretion of bioactive interleukin-1beta. Existence of a second cPOP provides additional insights into inflammasome formation and suggests that POPs might be a common regulatory mechanism to "fine-tune" the activity of specific PYD-NLR family protein-containing inflammasomes.

Catalogue number:	KTE61019
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	Q56P42
Gene:	152138
Additional info:	Human Pyrin domain-containing protein 2 (PYDC2) ELISA Kit has high sensitivity and excellent specificity for detection of Human PYDC2. No significant cross-reactivity or interference between Human PYDC2 and analogues was observed.

See Full Product Listings >

Human Pyrin domain-containing protein 2 (PYDC2) ELISA Kit

Cat no: KTE61019

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from Abbkine Scientific Co.Ltd.




By submitting this form you agree to your details being passed to Abbkine Scientific Co.Ltd. for the purpose of generating the best quote*